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Portfolio Manager, ESquared Assets
E Squared Capital, LLC
150 East 52nd Street, 22nd Floor
New York
United States of America
+1 (212) 235-0488
+1 (203) 940-0659
Bio/Company Profile:


Les Funtleyder is an experienced healthcare investor and analyst with a track record of significant positive returns across Pharmaceuticals, Medical Technology, Managed Care, Hospitals and other facilities, and Healthcare Information Technology utilizing public equity, private equity and debt. He has served as a speaker and resource to media, policymakers and corporations on the intersection of investing, health policy and innovation. Les is the author of Healthcare Investing: Profiting from the New World of Pharma, Biotech, and Health-Care Services (McGraw Hill, 2009).

Investment research, Investing using top-down (macro) and bottom up techniques, healthcare trends, healthcare policy, forecasting, valuation, risk management, public equity, private equity transactions, ETFs, index creation, impact investing, sustainability, African healthcare and hedging strategies.


Portfolio Manager- Healthcare

E Squared Asset Management
March 2014 – Present (1 year 6 months)Greater New York City Area

Manage the opportunistic healthcare portfolio for E Squared. Asset classes include long/short public equity, crossover investments, and venture capital.

Special Advisor

February 2014 – Present (1 year 7 months)San Francisco Bay Area

Popel(x) is the leading platform for providing investment opportunities and rich diligence in deep technology start-ups.

Chairman of the Board of Directors

Hexpro Analytics
December 2013 – Present (1 year 9 months)Greater Atlanta Area

Hexpro is one of the leading companies in the field of predictive analytics in healthcare. The company forecasts healthcare spending and utilization rates to assist investors in making optimal investment decisions and healthcare providers in making capital deployment decisions.

Consulting Partner

Blucloud Healthcare
December 2013 – Present (1 year 9 months)London, United Kingdom

Bluecloud is the leading incubator of Healthcare companies in sub-Saharan Africa. Services include Investment, capital formation and business development assistance.

Senior Advisor

HealthEngine LLC
December 2013 – Present (1 year 9 months)Greater Chicago Area

HealthEngine is the Uber and Priceline of healthcare. The company provides consumers with tools to break down asymmetries of information in healthcare providing tools to obtain the highest quality and lowest cost services.

Director of Strategic Investments

OPKO Health, Inc.
April 2014 – Present (1 year 5 months)Miami and NYC

Evaluate public and private companies for capital investments. Identify and acquire or companies that fit into Opko's strategic plan. Pursue licensing opportunities.


Boundless Impact Investing
June 2013 – Present (2 years 3 months)Greater New York City Area

Boundless is the premier learning community helping investors maximize the impact of their capital.

Managing Director

May 2012 – December 2013 (1 year 8 months)New York, New Yok

Helped develop a life science crowdfunding private equity platform. Also created ETFs in the healthcare sector.

Portfolio Manager

Modern Medicine Capital Advisors LLC
May 2012 – December 2013 (1 year 8 months)New York, New York

Portfolio Manager, Strategist, Miller Tabak Healthcare Transformation Fund

Miller Tabak
2004 – May 2012 (8 years)

• Created and managed the portfolio of the Miller Tabak Healthcare Transformation Fund (NASDAQ: MTHFX) a long/short equity, debt and private equity health care fund which produced double digit annual returns. The fund’s mandate was maximum risk adjusted returns across all sectors (pharmaceuticals, biotechnology, medical technology, managed care, hospitals, life science tools) both domestic and internationally. The fund used all parts of the capital structure including equity, debt, private equity and options to achieve its directive.
• Was an internationally-recognized media figure on healthcare investment, policy and innovation promoting the firm’s products and services.
• Produced widely-read strategy pieces that identified trends before most of the market, allowing for optimal capital deployment for equity, debt, option and private equity investors.
• Provided clients with econometric models to forecast health care spending, and its impact on health care providers in order to anticipate earnings and top line impacts of proposed policy changes.

Health Care Analyst, market neutral portfolio

Provident Advisors
March 2003 – March 2004 (1 year 1 month)Wyzata, Minnesota

Oversaw a market-neutral portfolio of healthcare assets delivering non-correlated, positive returns, using long and short positions. Used multiple parts of capital structure of investments to limit market risk of the portfolio. Assisted other teams at the firm with their healthcare investments including the volatility and private equity portfolios.

Analyst, Medical Technology and Medical Devices

UBS Investment Bank
June 1999 – February 2003 (3 years 9 months)

Published research on 20 medical technology and biotechnology stocks. Team was ranked on the WSJ top stock pickers. Participated in over 30 financing and acquisition transactions. Assisted in winning several corporate financing mandates

Biotechnology Analyst

Bigelow & company
June 1998 – June 1999 (1 year 1 month)Greater Denver Area

Published research on medical technology and biotechnology companies. Helped create an equity research department. Assisted in wining corporate finance mandates.

Buisness and clincal research

April 1996 – May 1998 (2 years 2 months)

Directed business and clinical research of a joint venture of Merck, Wyeth, and Medco. Was responsible for valuation and competitive intelligence of licensing, partnerships and acquisitions and other business development activities. Served as a product manager over several clinical projects.


Health Strategies Group
May 1995 – April 1996 (1 year)

Offered strategic advice to HMOs and hospitals

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